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Newsflash 1

Iontophoresis and Corneal Crosslinking: The Perfect Link?

 

 Iontophoresis

Dr. Prof. U.Menchini, Rita Mencucci

Transcutaneous medication delivery into tissues potentiated by an electrical current. The term Iontophoresis means ion transfer (Ionto = ion; phoresis = transfer).

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University of Florence Eye Clinic, Italy.


Entering the Lexicon of Treatment: Personalized Cross-linking 

Focused CXL

S. I. Anisimov, K. A. Zolotorevsky

 

Results of Corneal Ectasia Personalized Local Cross-linking Treatment

 

East-Sight Recover Eye Centre, Moscow, Russia.


A Demographic Profile of Corneal Transplantation Patients in Brazil

FPS

 FPS

Established in 2005 through a partnership between the Educational Foundation and Good Voyage Alice Figueira Support IMIP.

The Faculty of Health Pernambuco (FPS) has since been offering quality education in the areas of teaching and research.

 Cecilia M Cavalcanti, Ventura R, Cavalcanti BM, Cavalcanti RF
 
 
Over the Past 20 Years at a Northeast Brazil Eye Hospital
 
 
 

Faculty of Health Pernambucana, Recife, Pernambuco, Brazil.


 You Don't Need to Be the President to Change Your Country

 
2008- 2012 The Rise of the Foot Solider - A Delegation Mobilized for a Country
 
 
LifeAfterLasik.com gives a voice to Lasik casualties as an essential LASIK failure analysis platform for shared experiences with a growing advocacy involvement and knowledge base.
 
 LASIK is the most popular elective surgery, with more than 16 million procedures performed in the U.S. to date.  But in spite of high satisfaction rates, misconceptions and fears persist.
 
Covering countless amount of archived news stories that show the possible risks, side effects, and the potential quality of life issues to be aware that could be caused from every Lasik procedure (also the safety issues should be known about on other forms of vision correction such as contact lenses as well, and the safety ratio weighted up), before informed consent is given by a member of the general public. Also informing from the field on those direct complications that could be avoided if each patient was screened with mission critical safety and quality standards for any and all treatments.
 
Learn of how the founder and others like him have become permanently injured from this elective procedure, that is generally said to be safe and effective with no known long-term safety issues. When currently in the United States, Lasik is under scrutiny by Dr. Morris Waxler, Ex-FDA Chief of Medical Devices who has petitioned the FDA to have the FDA approval for Lasik withdrawn after he has heard from an endless stream of permanently injured Lasik patients asking him why he approved it…
 
 
 
Life after Lasik
 
 
Its Left To The Man On The Street To Change Policy
 
 
 
 
Dean Andrew Kantis Founder and Prevention of Lasik Casualties Advocate.

 
Nope, None, Nothing, Naught, Nish, Nowt, Nix, Nay, Non, Null, Nil, Nada...
 
...Zip, Zippo, Zero, Zilch, Diddly, No Contact Lenses or Glasses Required.
 
 
Slovak University of Technology
 
Class of 2012 Celebrating Graduation and Students No Vision Restriction
 
 The Slovak University of Technology is the Largest Technology University in Slovakia
 
 
Treatment of Pellucid Marginal Degeneration
 
Simultaneous Excimer Laser Ablation and CXL
 
 
 
 Tomas Juhas, MD, OFTUM – laser refractive surgery center, Košice, Slovakia.

Transepithelium Crosslinking Under the International Microscope

 
Universitätsklinikum Dresden
 
 
Eberhard Spoerl, PhD.
 
Transepithelial Crosslinking - Where are we ?
 

Department of Ophthalmology , University Hospital Dresden, Germany.


 Northern Ireland: Owen’s Family Launch Fight to Save His Sight

Keratoconus - Save My Site

'Save My Sight'

“We’ve found the standard of care from the health service to be poor. Their normal procedure is to fit contacts and watch how things progress. I thought there would have been more of a rush.”

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Published by Portadown Times.


Changes in Corneal Characteristics following Crosslinking compared with T - CAT prior to Crosslinking

Dr. Prema Padmanabhan
Dr. Bhaskar Srinivasan
Ms. Aiswaryah
Ms. Abinayapriya
Dr. Nidhi Gupta

CXL Vs Topographic Customized Ablation Treatment (T-CAT) + CXL

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Medical Research Foundation, Sankara Nethralaya Eye Hospital Charitable Trust, Chenni, India.

Sankara Nethralaya

“Best Hospital in Ophthalmology in India 2010" - The ICICI Lombard/CNBC TV-18 Award.

“Best Hospital in Ophthalmology in India 2010" - The Week/Hansa Research.
 
“Best Hospital in Ophthalmology in India 2011" - The Week/Hansa Research.
 
 

 
Corneal Cross-linking now a well Established Practice in the Asia-Pacific Region
 
 Petronas Twin TowersRegions Kids
 25thNational Eye Hospital
 
 Corneal collagen cross-linking, which began in Europe more than a decade ago, is now a well-established practice in the Asia-Pacific region.
 
 
Published by Ocular Surgery news, the official news publication of the Asia-Pacific Academy of Ophthalmology.
 

AXL from the Pioneers of Crosslinking: Ethics Approved for the Next Level of Crosslinking Science

AXL TeamCXL Congress

Rebecca McQuaid - Along with being an Ophthalmic Technician and Research Assistant, Rebecca is currently undertaking a Masters Degree in Physics and Cornea Diagnostics, sponsored by the Wellington Eye Clinic, at University College Dublin.

Maria Galligan BSc – In conjunction with being at the forefront of vision services at the Wellington Eye Clinic, Maria works with the Clinic in association with the National Digital Research Council, as well as the Dublin Institute of Technology.

Rebecca presents Accelerated Corneal Crosslinking - at the 7th annual Corneal Cross-Linking Congress. It was a presentation which was highly received by the congressional audience, with many of the great names in Ophthalmology in attendance.

Rebecca actively works with a team of respected international experts in the field, including principal figures such as Professor Michael Mrochen in Zürich, Switzerland, and Dr. Prema Padmanabhan in Chennai, India.

 
The Wellington Eye Clinic introduces Accelerated Corneal Cross-Linking. - AXL - The leading edge of Crosslinking Science and its Optimization since its Invention. Fully mindful accuracy in evidence based medicine to fully wining Ethics Approval - for the procedure time to be reduced from 30 minutes to 10 minutes, by using a CE approved higher intensity Ultra-Violet lamp.
 
 

  KC Patients: The Inbetweeners - Stuck In The Middle with Keratoconus
 
Sandy
 
'Going Blind Waiting'
 
 At first, Sandy Weatherhead dismissed her blurred vision as just a normal part of the aging process. "I thought 'Oh, I'm getting old. I need glasses," the 41-year-old Simcoe woman said. A couple of doctor's appointments later, Weatherhead learned her situation was far worse...
 
 
Published by Simcoe Reformer.

Keraflex: The World’s First Treatment to Correct KC Corneas without Any Cutting
 
The application of heat for Keratoconus at limited centers, continues the research in its use until it matches patient expectations. As the only, quick to perform, non-surgical, non-invasive treatment for Keratoconus that reshapes the cornea without tissue removal which is required completely in a transplant.
 
 
...that’s the mystery of grace, it never comes too late.
 ...that’s the mystery of grace, it never comes too late.
 

Sylvia Paulig MD 

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Paulig Augenklinik|Praxis Bahnhofstr 60 03046 Cottbus & Friedrichstr 89 10117 Berlin, Germany.

 
Rescue Today and Rescue Tomorrow: Exceptional Evidence Based Medicine Delivery
 
The CXL Congress Award Winning Presentation
 
 
CXL with or without epithelial abrasion:  Is there any difference in corneal biomechanics?
 
 
Exceptional Delivery
 
'Exceptional Delivery'
 
 
Eberhard Spoerl, PhD, Frederik Raiskup-Wolf, MD.

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Department of Ophthalmology, University Hospital Dresden, Germany.
 

In memory of Dr. Newton Wesley: A KC Patient who Pioneered Contact Lenses

 

"Wesley was way ahead of his time and pioneered the use of contact lenses that helped himself see with his KC - when he was told to learn Braille".


I heard of the passing of Dr. Newton Wesley from Morgan Wesley, Dr. Newton Wesley's son. Newton was one of the pioneers of contact lens field in the 1950s and early 1960s. His National Eye Research Foundation and his personally founded and promoted myopia control, Orthokeratology, and Keratoconus research - because Newton himself had KC.

He never needed a transplant when there was times he went to over 12 different ECPs all over the United States to get contact lenses which fitted, but for one reason or another they failed each time to work correctly (which is the experience for KC patients in general). However, he learnt from the failures and that eventually got him contact lenses that fit him comfortably…fitting flat to align the superior intermediate area of his KC with rigid lenses, which is what he wore into his 90s. Its the fitting which I learnt from him for Keratoconus (with results no soft lens to this day can achieve).

He was his own man and marched to a different drummer, which innovators and pioneers must do to get their innovations accepted worldwide. He was even on the “Tonight Show” (with Steve Allen as host), promoting contact lenses. He did his own research and promotions which helped develop the field and built the W&J Contact Lens Company.

I was proud to know Newton and lecture at the Newton's NERF conferences in Las Vegas. He was a giant and a leader in innovation and promotion of the contact lens industry, when he and Dr. George Jessen started the W&J Contact Lens Company that CIBA eventually bought out. I have passed our respects on to his son. In my humble opinion without Newton's influence there would be no Orthokeratology field acceptance today.

I considered Newton a teacher and mentor in my research of Keratoconus and practicing DW Ortho-k in the late 70s. I was lucky to know him and learnt from him at his NERF conferences. I hope his family's grieving will be as brief as possible. Newton was a mensch (a warm and caring human being). He saw the big picture. In my view - all men and women who see the big picture will go to a much higher place. RIP.

Jeff Eger,OD FIOS
Mesa. AZ.
 
 

 
The Jakarta Globe - More Choosing Partial Cornea Transplants in Singapore
 
Partial

The 20-year-old son of MediaCorp artists Edmund Chen and Xiang Yun underwent a cornea transplant recently after a contact lens infection six years ago had badly affected vision in his left eye.

 

 
The Morphologic Characteristics of Corneal Nerves in Advanced KC as Evaluated by Acetylcholinesterase Technique
 
Al-Aqaba MA, Faraj L, Fares U, Otri AM, Dua HS.
 
Department of Surgery, College of Medicine, The University of Basrah, Basrah, Republic of Iraq.
 
Purpose: To study the morphologic characteristics of corneal nerves in patients with advanced keratoconus using the acetylcholinesterase technique in corneal whole mounts.

Design: Prospective, observational case series.

Methods: Fourteen corneal buttons from 14 keratoconic patients (9 males and 5 females; mean age, 34.3 years) who had undergone keratoplasty for advanced keratoconus and 6 corneal buttons from 6 normal corneas were included. Whole mounts were stained for acetylcholinesterase and were scanned with a novel digital pathology scanning microscope.

Results: Seventy-one percent of keratoconic corneas demonstrated central stromal nerve changes, which included thickening, tortuosity, nerve spouting, and overgrowth. The nerve changes ranged from early to extensive and could be separated into 3 different grades. The central stromal nerves were abnormally thicker (18.9 ± 14.7 μm) than in controls (8.11 ± 3.31 μm; P < .001). The thickness of peripheral stromal nerves (12.6 ± 3.1 μm) was similar to that of controls (14.86 ± 5.60 μm; P = .072). Subbasal nerves showed changes in the form of loss of radial orientation and increased tortuosity, especially at the cone apex. At the cone base, a concentric arrangement of subbasal nerves was found in 43% of cases. Localized thickenings of subbasal nerves also were observed at their origin from the bulbous terminations of sub-Bowman nerves. The terminal bulbs, too, were enlarged. The mean diameter of the subbasal nerves in keratoconus (4.11 ± 0.60 μm) did not differ from that of the controls (4.0 ± 0.61 μm; P = .422).
 
Conclusions: This study provides additional histologic evidence of the involvement of corneal nerves in keratoconus and suggests further that they may play a role in the pathophysiologic factors and progression of the disease.
 
Am J Ophthalmol.

 Analyzing Keratoconus Susceptibility and Advancement: A Stitch in Time Saves Nine
 
 Keratoconus Team Malaysia
 
 How many unknowingly has or suffer from Keratoconus in Malaysia ?
 
Since May 2010 the Department of Molecular Biology at the University of Malaya, as well carrying out Genetic Studies into Keratoconus, has started screening for Keratoconus.
 
The research will cover the hereditary predisposition to Keratoconus and the susceptibility factors, including their functional characteristics and impact on the risk and the behavior of Keratoconus.
 
Two screening programs were done in Klang last year, and two have already have been done in Ipoh and Penang this year.
 
The team from the University of Malaya is headed by Prof MaryAnne Tan and Dr Rozaida Poh in association with Dr Jenny P Deva.
 
In Ipoh the screening was done at the Ipoh Specialist Hospital in cooperation with Dr Lam Fook Shim.
 
In Penang screening sessions was held at the Adventist Specialist Hospital in cooperation with Dr Tah  Kheng Soon.
 
Our Ambulant Screening Team in Malaysia is pictured below with Dr Tah, which also includes two Nurses, two BSc Students and one Technician.
 
Keratoconus Team Malaysia
 
Keratoconus Team Malaysia
 
Keratoconus Team Malaysia

  


 The Avedro Vedera KXS: Gold Winner of the Medical Device Excellence Award 2011  
 Vedera KXS
The Award Winning Avedro Vedera KXS Vision Correction Device
 
Avedro’s Vedera System® Wins Gold in the Medical Design Excellence Award.
 
 
Microwave Thermokeratoplasty with Corneal Collagen Cross-linking used to Treat Keratoconus
 
Studies of the combined procedure are currently under way in Europe and Turkey

 

 
The Lifetime Economic Burden of KC: A Decision Analysis Using a Markov Model
 
Rebenitsch RL, Kymes SM, Walline JJ, Gordon MO
 
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri.

Purpose: To estimate the expected incremental lifetime cost of treatment of keratoconus compared to the expected cost of the treatment of myopia.
 
Design: Cost estimate from the patient's perspective using a Markov decision model.
 
Methods: We modeled a hypothetical cohort of people with clinically significant incident keratoconus as defined by the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study. We included costs of clinic visits, fitting fees, contact lenses, surgical procedures, and complications. Survival curves of corneal transplants and associated complications were modeled using data from the 2007 Australian Graft Registry. Medical treatment regimens after surgery were defined by expert opinion.
 
Results: The expected value of the lifetime cost of the treatment of keratoconus over myopia was $25 168 with a standard deviation of $16 247 and a median of $17 596. The factors that most influenced the lifetime cost were the probability of initial corneal transplant and a subsequent regraft. The cost of routine care had relatively little influence on the lifetime cost of care.
 
Conclusions: The expected lifetime cost of treatment of keratoconus represents a significant cost to patients and payors. While the cost of routine care for keratoconus is not trivial, the primary factor influencing changes in the cost of care for keratoconus is the probability of corneal transplant. Combined with the significantly impaired vision-related quality of life and the relatively young onset of disease, the economic burden of the treatment of keratoconus represents a significant public health concern.
Am J Ophthalmol.

Something to shout about: The 6th International Congress of Corneal Cross-linking.

Milan, Italy, January 21 & 22, 2011.
 
The International Corneal Crosslinking Congress specializes in developing intuition in original thoughts and solutions to really maximize every patients visual potential, where ever they may be asking for more in the world.
 
The International Corneal Crosslinking Congress is where new breakthrough developments are independent from market forces, which in the end is what really gives patients maximum flexibility. What makes the International Corneal Crosslinking Congress unique is the experienced globe trotting in-house development teams, translating complex Keratoconus parameter requirements into deliverable benefits – where time to vision is crucial.
 
The International Corneal Crosslinking Congress are an experienced team of academics, medical and science driven professionals with industry leading innovators, specializing in visual need projection, implementing patient/clinical/medical and industry-scale future proofing care - a robust and accurate road map that is equipping us for the future, for happiness now. The people who make the International Corneal Crosslinking Congress what it has become today, come from culturally rich, diverse backgrounds, equals proficient in their fields who are highly determined to come together for the one wide-ranging quality they all have in common - the ability to deliver.
 
Listening and truly understanding each patient's visual requirements, medically and technically, allows us to provide innovative solutions. In order to attain this goal, at the International Corneal Crosslinking Congress, all the relevant aspects of modern corneal sciences was open for insightful analysis to enable and accelerate technological advancement. We are - Justifying Technologies - which translates into tangible benefits for patients; increased quality of care, an enhancement in freedom not feardom, cost reduction, getting your life back and speed to vision.
 
 
Below are the words to the 'three pillars' of the Global Keratoconus Foundation.
 
 
CREATIVITY

Always relishing a challenge, we are constantly exploring innovative ideas.

RESPONSIBILITY

Always wanting to remove the two letters “i” and “m” from the word impossible – so making the impossible, a possible. Our real work is all about solving problems.

COMMITTMENT

Always putting ourselves in the patients' position and then thinking about what we can do for them.
 
kcglobalA Good Sign 
 

 
Topo-aberrometric, Refractive and Pachymetric analysis of Keratoconics eyes undergoing CXL
 
Paolo Vinciguerra M.D.
E. Albé M.D.
S. Trazza Orthottist.

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Istituto Clinico Humanitas, University of Milan, Italy.
 

Live National Webcast on the 21st of October at 12:30 pm EST

 From this autumn there will be a series of National Webcasts
featuring first's on subjects such as
"Not a Lasik candidate", to a broadcast special on "Keratoconus"
 
Which can be seen at the Channel 4 website live
by logging on to news4jax.com
at 12:30 pm EST on the 21st of October
 
 

 Arun C. Gulani, M.D., M.S. will be answering questions submitted during this Webcast and others to follow, so you may send questions in advance by e-mailing:

This email address is being protected from spam bots, you need Javascript enabled to view it
 
 
 

When the Result Is Greater Than the Sum of the Parts

David Jory MBBS FRCOphth, Consultant Ophthalmologist
Advanced Surgery Center, The Technology Park, London.
 
CXL
 
CXL in the Treatment of Acute Post-Lasik Ectasia
 
 
 
Fellow of the Royal College of Ophthalmologists, Fellow of the Royal Society of Medicine, and Fellow of the Medical Society of London. 
Teaching faculty member of the American Society of Cataract & Refractive Surgery, and the European Society of Cataract & Refractive Surgeons.

 
Effects of Corneal Collagen Crosslinking on Corneal Topography, Visual Acuity and Contrast Sensitivity
 
Camila Netto MD ; Bruno Procópio MD ;
Ricardo Gomes dos Reis MD ; Mariana Pecego MD ; Lorena Vianna ;
Haroldo Vieira de Moraes Jr. MD, PhD ; Adalmir Morterá Dantas MD, PhD.

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Federal University of Rio de Janeiro, Brazil.

 
The World Ophthalmology Congress (WOC) Berlin 2010
 
 
The 32nd International Congress of Ophthalmology, the World Ophthalmology Congress (WOC) is the largest international congress of ophthalmology.
 
 WOC® 2010 awards medals to outstanding ophthalmologists

In the spirit of achievement and excellence at WOC 2010, Bruce Spivey, president of the International Council of Ophthalmology (ICO) awarded five ophthalmologists with medals for their outstanding work.

The prestigious Gonin Medal went to Dr Alan Charles Bird.

The International Duke Elder Medal was awarded to Dr Mohammad Daud Khan.

The Jules Francois Golden Medal went to Dr Gisele Soubrane, the first woman to ever receive a medal from the international council.

The ICO Ophthalmic Pathology Award went to Dr Ursula Schlotzer-Schrehardt.

Finally, Prof Peter G Watson, the current Academia Ophthalmologica Internationalis (AOI) president gave the Bernardo Streiff Gold Medal to Dr Gullapalli N Rao.
 

The Russian Hungarian Connection: Doctor Artsybashev Vs Keratoconus

 
Covered by our International News Correspondent

 Peter Goren

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Peter Goren is an American medical student at Semmelweis University in Budapest, Hungary.

 

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