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Newsflash 1

Keratoconus and the Book of Power: Speaking In Tongues


 Important new textbook on little known but prevalent eye disease

Wellington Eye Clinic, Level 2, 36 Beacon Hall, Beacon Court, Dublin City, D18 T8P3, Ireland. +353 12 930 470.

Clinical Performance of Toris K - Soft Silicone Hydrogel Contact Lens
In Patients with Moderate to Advanced Keratoconus:
 A Real Life Retrospective Analysis.

What if patients start advising the doctor ?


Beyoglu Eye Training and Research Hospital, 34420 Istanbul, Turkey.

Long-term follow-up results of Corneal Collagen Cross-linking

Keratokonusta korneal kollajen çapraz-bağlama tedavisinin uzun dönem sonuçları
Acibadem University School of Medicine Ophthalmology Department İstanbul, Turkey.
Dunya Goz Hospital, Etiler, İstanbul, Turkey.

Human Keratoconus Cell Contractility is Mediated
by Transforming Growth Factor-Beta Isoforms
Floating 3D Gel
 Floating 3D-collagen gel seeded with untreated control (A) human corneal
fibroblasts (HCFs) and (B) human keratoconus cells (HKCs). Change in area of the collagen
gel was measured every other day using ImageJ software. Representative images shown, n = 3.

Laserfit: Wavefront Optics Simplified

Dr. Gemoules
Dr. Gregory Gemoules

'Similar to a mythical unicorn, contact lenses with wavefront-guided optics was something people liked to talk about, but nobody had ever seen.

A soft lens version became available, but the results were not what was needed for our patients. So what about doing a wavefront-guided surface on a Scleral lens?'

Dr. Gregory Gemoules, Laserfit, 712 S. Denton Tap Road Coppell, TX 75019, USA.

Biomechanics of the Cornea

Corneal Stroma Lamella

Have we gained the control over corneal biomechanics?


George D.. Kymiioniis MD, PhD. Institute of Vision and Optics University of Crete School of Medicine Heraklion, Greece.

CXL Using Different Devices

Avedro Interface


Arthur Cummings FRCSEd. Wellington Eye Clinic, Dublin, Ireland

Optimization Pathways of CXL

Optimised Beam Profile
 Optimised Beam Profile


Biophysical Processes

Diffusion, Intensity and Beam Profile.

Everything is closer now


    University College Dublin and Wellington Eye Clinic, Dublin, Ireland.

Epi-on and Epi-off CXL Applications

 Universiteit Antwerpen
 University Hospital Antwerp


Koppen C MD, PhD
Antwerp, Belgium.

Not all Transepithelial CXL is Equal

More peer reviewed basic and clinical studies are needed.


1. University of Antwerp. 2. University Hospital Antwerp.

 Corneoplastique™: Art of Vision Surgery

Innovations by Dr Gulani

 Indian J Ophthalmol is the Official Scientific Journal of the All India Ophthalmological Society (AIOS)

'This concept of approaching each case individually and designing vision therewith enables surgeons to correct not only virgin eyes but also approach complex cases and complications with the goal of 20/20 vision.'

 Corneoplastique™ -  Indian J Ophthalmol 



Gulani Vision Institute, 8075 Gate Parkway (W), Suite 102, Jacksonville, Florida 32216, USA.

Superior Technical and Scientific Achievement 'Arms Race'

Technology-ready: In this rapidly shifting and expanding patient care landscape, there is a corresponding arms race, and a triumph.


UV-X 2000


Advantages of the UV-X™ 2000 System

  • Optimized beam profile
  • Larger volume of cross-linked corneal tissue
  • Shorter treatment time
  • New distance control
  • Negligible illumination leakage

UV-X™ 2000 device is the first CXL illumination device which features an optimized beam profile to maximize the cross-linking volume.


Is Iatrogenic Keratectasia influenced by Estrogens?

Time Course

Changes in Kmax readings - Time Course

Farhad Hafezi, MD PhD

Changes of estrogen levels during pregnancy

 Reduce the biomechanical stability of the cornea.

 Might represent a previously unrecognized risk factor for Iatrogenic Keratectasia.


Risk factors for Iatrogenic Keratectasia



IROC, Institute for Refractive and Ophthalmic Surgery, Zurich, Switzerland.

Simply Eye Catching: Laser Vision Screening

 Counting Numbers

Unmasking the real KC incidence - Lets put counting fingers in to a museum.


Test. Treat. Track. Laser Vision Clinics Efficient Surveillance & Elimination of Keratoconus



 Khatam-Al-Anbia Eye Hospital, Mashhad University of Medical Sciences, Mashad, Iran.

Combined LASIK and Rapid-CXL in Suspicious Corneas



 Victor Derhartunian , Theo Seiler

To evaluate a new surgical technique combining FemtoLASIK and Rapid Crosslinking


 Institut für Refraktive und Ophthalmo-Chirurgie (IROC), Zurich, Switzerland.

Iontophoresis and Corneal Crosslinking: The Perfect Link?


Dr. Prof. U.Menchini, Rita Mencucci

Transcutaneous medication delivery into tissues potentiated by an electrical current. The term Iontophoresis means ion transfer (Ionto = ion; phoresis = transfer).


University of Florence Eye Clinic, Italy.

Entering the Lexicon of Treatment: Customized Cross-linking 

Focused CXL

S. I. Anisimov, K. A. Zolotorevsky


Results of Corneal Ectasia Personalized Local Cross-linking Treatment


East-Sight Recover Eye Centre, Moscow, Russia.

A Demographic Profile of Corneal Transplantation Patients in Brazil



Established in 2005 through a partnership between the Educational Foundation and Good Voyage Alice Figueira Support IMIP.

The Faculty of Health Pernambuco (FPS) has since been offering quality education in the areas of teaching and research.

 Cecilia M Cavalcanti, Ventura R, Cavalcanti BM, Cavalcanti RF
Over the Past 20 Years at a Northeast Brazil Eye Hospital

Faculty of Health Pernambucana, Recife, Pernambuco, Brazil.

 You Don't Need to Be the President to Change Your Country

2008- 2012 The Rise of the Foot Solider - A Delegation Mobilized for a Country
LifeAfterLasik.com gives a voice to Lasik casualties as an essential LASIK failure analysis platform for shared experiences with a growing advocacy involvement and knowledge base.
 LASIK is the most popular elective surgery, with more than 16 million procedures performed in the U.S. to date. But in spite of high satisfaction rates, misconceptions and fears persist.
Covering countless amount of archived news stories that show the possible risks, side effects, and the potential quality of life issues to be aware that could be caused from every Lasik procedure (also the safety issues should be known about on other forms of vision correction such as contact lenses as well, and the safety ratio weighted up), before informed consent is given by a member of the general public. Also informing from the field on those direct complications that could be avoided if each patient was screened with mission critical safety and quality standards for any and all treatments.
Learn of how the founder and others like him have become permanently injured from this elective procedure, that is generally said to be safe and effective with no known long-term safety issues. When currently in the United States, Lasik is under scrutiny by Dr. Morris Waxler, Ex-FDA Chief of Medical Devices who has petitioned the FDA to have the FDA approval for Lasik withdrawn after he has heard from an endless stream of permanently injured Lasik patients asking him why he approved it…
Life after Lasik
Its Left To The Man On The Street To Change Policy
Dean Andrew Kantis Founder and Prevention of Lasik Casualties Advocate.

Nope, None, Nothing, Naught, Nish, Nowt, Nix, Nay, Non, Null, Nil, Nada...
...Zip, Zippo, Zero, Zilch, Diddly, No Contact Lenses or Glasses Required.
Slovak University of Technology
Class of 2012 Celebrating Graduation and Students No Vision Restriction
 The Slovak University of Technology is the Largest Technology University in Slovakia
Treatment of Pellucid Marginal Degeneration
Simultaneous Excimer Laser Ablation and CXL
 Tomas Juhas, MD, OFTUM – laser refractive surgery center, Košice, Slovakia.

Transepithelium Crosslinking Under the International Microscope

Universitätsklinikum Dresden
Eberhard Spoerl, PhD.
Transepithelial Crosslinking - Where are we ?

Department of Ophthalmology , University Hospital Dresden, Germany.

 Northern Ireland: Owen’s Family Launch Fight to Save His Sight

Keratoconus - Save My Site

'Save My Sight'

“We’ve found the standard of care from the health service to be poor. Their normal procedure is to fit contacts and watch how things progress. I thought there would have been more of a rush.”


Published by Portadown Times.

Changes in Corneal Characteristics following Crosslinking compared with T - CAT prior to Crosslinking

Dr. Prema Padmanabhan
Dr. Bhaskar Srinivasan
Ms. Aiswaryah
Ms. Abinayapriya
Dr. Nidhi Gupta

CXL Vs Topographic Customized Ablation Treatment (T-CAT) + CXL


Medical Research Foundation, Sankara Nethralaya Eye Hospital Charitable Trust, Chenni, India.

Sankara Nethralaya

“Best Hospital in Ophthalmology in India 2010" - The ICICI Lombard/CNBC TV-18 Award.

“Best Hospital in Ophthalmology in India 2010" - The Week/Hansa Research.
“Best Hospital in Ophthalmology in India 2011" - The Week/Hansa Research.

Corneal Cross-linking now a well Established Practice in the Asia-Pacific Region
 Petronas Twin TowersRegions Kids
 25thNational Eye Hospital
 Corneal collagen cross-linking, which began in Europe more than a decade ago, is now a well-established practice in the Asia-Pacific region.
Published by Ocular Surgery news, the official news publication of the Asia-Pacific Academy of Ophthalmology.

AXL from the Pioneers of Crosslinking: Ethics Approved for the Next Level of Crosslinking Science

AXL TeamCXL Congress

Rebecca McQuaid - Along with being an Ophthalmic Technician and Research Assistant, Rebecca is currently undertaking a Masters Degree in Physics and Cornea Diagnostics, sponsored by the Wellington Eye Clinic, at University College Dublin.

Maria Galligan BSc – In conjunction with being at the forefront of vision services at the Wellington Eye Clinic, Maria works with the Clinic in association with the National Digital Research Council, as well as the Dublin Institute of Technology.

Rebecca presents Accelerated Corneal Crosslinking - at the 7th annual Corneal Cross-Linking Congress. It was a presentation which was highly received by the congressional audience, with many of the great names in Ophthalmology in attendance.

Rebecca actively works with a team of respected international experts in the field, including principal figures such as Professor Michael Mrochen in Zürich, Switzerland, and Dr. Prema Padmanabhan in Chennai, India.

The Wellington Eye Clinic introduces Accelerated Corneal Cross-Linking. - AXL - The leading edge of Crosslinking Science and its Optimization since its Invention. Fully mindful accuracy in evidence based medicine to fully wining Ethics Approval - for the procedure time to be reduced from 30 minutes to 10 minutes, by using a CE approved higher intensity Ultra-Violet lamp.

  KC Patients: The Inbetweeners - Stuck In The Middle with Keratoconus
'Going Blind Waiting'
 At first, Sandy Weatherhead dismissed her blurred vision as just a normal part of the aging process. "I thought 'Oh, I'm getting old. I need glasses," the 41-year-old Simcoe woman said. A couple of doctor's appointments later, Weatherhead learned her situation was far worse...
Published by Simcoe Reformer.

Keraflex: The World’s First Treatment to Correct KC Corneas without Any Cutting
The application of heat for Keratoconus at limited centers, continues the research in its use until it matches patient expectations. As the only, quick to perform, non-surgical, non-invasive treatment for Keratoconus that reshapes the cornea without tissue removal which is required completely in a transplant.
...that’s the mystery of grace, it never comes too late.
 ...that’s the mystery of grace, it never comes too late.

Sylvia Paulig MD 

Click Here

Read More 

Paulig Augenklinik|Praxis Bahnhofstr 60 03046 Cottbus & Friedrichstr 89 10117 Berlin, Germany.

Rescue Today and Rescue Tomorrow: Exceptional Evidence Based Medicine Delivery
The CXL Congress Award Winning Presentation
CXL with or without epithelial abrasion:  Is there any difference in corneal biomechanics?
Exceptional Delivery
'Exceptional Delivery'
Eberhard Spoerl, PhD, Frederik Raiskup-Wolf, MD.

Click Here

Read More

Department of Ophthalmology, University Hospital Dresden, Germany.

In memory of Dr. Newton Wesley: A KC Patient who Pioneered Contact Lenses


"Wesley was way ahead of his time and pioneered the use of contact lenses that helped himself see with his KC - when he was told to learn Braille".

I heard of the passing of Dr. Newton Wesley from Morgan Wesley, Dr. Newton Wesley's son. Newton was one of the pioneers of contact lens field in the 1950s and early 1960s. His National Eye Research Foundation and his personally founded and promoted myopia control, Orthokeratology, and Keratoconus research - because Newton himself had KC.

He never needed a transplant when there was times he went to over 12 different ECPs all over the United States to get contact lenses which fitted, but for one reason or another they failed each time to work correctly (which is the experience for KC patients in general). However, he learnt from the failures and that eventually got him contact lenses that fit him comfortably…fitting flat to align the superior intermediate area of his KC with rigid lenses, which is what he wore into his 90s. Its the fitting which I learnt from him for Keratoconus (with results no soft lens to this day can achieve).

He was his own man and marched to a different drummer, which innovators and pioneers must do to get their innovations accepted worldwide. He was even on the “Tonight Show” (with Steve Allen as host), promoting contact lenses. He did his own research and promotions which helped develop the field and built the W&J Contact Lens Company.

I was proud to know Newton and lecture at the Newton's NERF conferences in Las Vegas. He was a giant and a leader in innovation and promotion of the contact lens industry, when he and Dr. George Jessen started the W&J Contact Lens Company that CIBA eventually bought out. I have passed our respects on to his son. In my humble opinion without Newton's influence there would be no Orthokeratology field acceptance today.

I considered Newton a teacher and mentor in my research of Keratoconus and practicing DW Ortho-k in the late 70s. I was lucky to know him and learnt from him at his NERF conferences. I hope his family's grieving will be as brief as possible. Newton was a mensch (a warm and caring human being). He saw the big picture. In my view - all men and women who see the big picture will go to a much higher place. RIP.

Jeff Eger,OD FIOS
Mesa. AZ.

The Jakarta Globe - More Choosing Partial Cornea Transplants in Singapore

The 20-year-old son of MediaCorp artists Edmund Chen and Xiang Yun underwent a cornea transplant recently after a contact lens infection six years ago had badly affected vision in his left eye.


The Morphologic Characteristics of Corneal Nerves in Advanced KC as Evaluated by Acetylcholinesterase Technique
Al-Aqaba MA, Faraj L, Fares U, Otri AM, Dua HS.
Department of Surgery, College of Medicine, The University of Basrah, Basrah, Republic of Iraq.
Purpose: To study the morphologic characteristics of corneal nerves in patients with advanced keratoconus using the acetylcholinesterase technique in corneal whole mounts.

Design: Prospective, observational case series.

Methods: Fourteen corneal buttons from 14 keratoconic patients (9 males and 5 females; mean age, 34.3 years) who had undergone keratoplasty for advanced keratoconus and 6 corneal buttons from 6 normal corneas were included. Whole mounts were stained for acetylcholinesterase and were scanned with a novel digital pathology scanning microscope.

Results: Seventy-one percent of keratoconic corneas demonstrated central stromal nerve changes, which included thickening, tortuosity, nerve spouting, and overgrowth. The nerve changes ranged from early to extensive and could be separated into 3 different grades. The central stromal nerves were abnormally thicker (18.9 ± 14.7 μm) than in controls (8.11 ± 3.31 μm; P < .001). The thickness of peripheral stromal nerves (12.6 ± 3.1 μm) was similar to that of controls (14.86 ± 5.60 μm; P = .072). Subbasal nerves showed changes in the form of loss of radial orientation and increased tortuosity, especially at the cone apex. At the cone base, a concentric arrangement of subbasal nerves was found in 43% of cases. Localized thickenings of subbasal nerves also were observed at their origin from the bulbous terminations of sub-Bowman nerves. The terminal bulbs, too, were enlarged. The mean diameter of the subbasal nerves in keratoconus (4.11 ± 0.60 μm) did not differ from that of the controls (4.0 ± 0.61 μm; P = .422).
Conclusions: This study provides additional histologic evidence of the involvement of corneal nerves in keratoconus and suggests further that they may play a role in the pathophysiologic factors and progression of the disease.
Am J Ophthalmol.

 Analyzing Keratoconus Susceptibility and Advancement: A Stitch in Time Saves Nine
 Keratoconus Team Malaysia
 How many unknowingly has or suffer from Keratoconus in Malaysia ?
Since May 2010 the Department of Molecular Biology at the University of Malaya, as well carrying out Genetic Studies into Keratoconus, has started screening for Keratoconus.
The research will cover the hereditary predisposition to Keratoconus and the susceptibility factors, including their functional characteristics and impact on the risk and the behavior of Keratoconus.
Two screening programs were done in Klang last year, and two have already have been done in Ipoh and Penang this year.
The team from the University of Malaya is headed by Prof MaryAnne Tan and Dr Rozaida Poh in association with Dr Jenny P Deva.
In Ipoh the screening was done at the Ipoh Specialist Hospital in cooperation with Dr Lam Fook Shim.
In Penang screening sessions was held at the Adventist Specialist Hospital in cooperation with Dr Tah  Kheng Soon.
Our Ambulant Screening Team in Malaysia is pictured below with Dr Tah, which also includes two Nurses, two BSc Students and one Technician.
Keratoconus Team Malaysia
Keratoconus Team Malaysia
Keratoconus Team Malaysia



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